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How is DMT made?: You could also potentially test the levels of DMT in someone who is having a near-death experience, or look at the expression of the gene that's responsible for the synthesis of DMT in dying people. Strassman said there is some unpublished data that indicates DMT levels increase in the brain in dying animals. If research in this area is looked into further, the connection could be strengthened, he said. As for where DMT research could go in the future, Strassman said it could help us define certain aspects of consciousness. "I thought to myself that I must try DMT as a last ditch effort before committing to the plan of suicide. Luckily for me the outcome was better than I could've imagined and I can say that it really did save my life," he said. "I believe DMT can be utilised in a therapeutic setting as a revolutionary treatment used to heal people... The world is changing and I think we're entering a new era of human civilization." When smoked, DMT produces brief yet intense visual and auditory hallucinations that have been described by users as an alternate reality, otherworldly, or a near-death experience. In comparison to other psychedelic drugs, such as LSD, ketamine, and magic mushrooms, recreational users of DMT consider it to have the lowest side effect profile. Possible side effects of DMT include: increased heart rate increased blood pressure chest pain or tightness agitation dilated pupils rapid rhythmic movements of the eye dizziness. There is some evidence that DMT is also produced endogenously, in other words, it is produced naturally in the body, specifically in the pineal gland in the brain. When smoked, the average dose of DMT is believed to be somewhere between 30 to 150 milligrams (mg), and the onset of action can be felt almost instantly. The effects peak and plateau for 3 to 5 minutes, and gradually drop off with the duration of effect totaling 30 to 45 minutes. When consumed as a brew, the dose is between 35 to 75 mg. Effects begin after 30 to 45 minutes, peak after 2 to 3 hours and are resolved in 4 to 6 hours. - [Read More]